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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNA2
All Species:
30.91
Human Site:
T383
Identified Species:
61.82
UniProt:
P20248
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20248
NP_001228.1
432
48537
T383
L
I
R
K
T
G
Y
T
L
E
S
L
K
P
C
Chimpanzee
Pan troglodytes
XP_517420
432
48476
T383
L
I
R
K
T
G
Y
T
L
E
S
L
K
P
C
Rhesus Macaque
Macaca mulatta
XP_001100860
432
48504
T383
L
I
R
K
T
G
Y
T
L
E
S
L
K
P
C
Dog
Lupus familis
XP_540965
432
48633
T383
L
V
Q
K
T
G
Y
T
L
E
S
L
K
P
C
Cat
Felis silvestris
Mouse
Mus musculus
P51943
422
47265
T373
L
A
Q
Q
T
G
Y
T
L
E
S
L
K
P
C
Rat
Rattus norvegicus
Q6AY13
421
47676
S371
L
A
A
F
T
G
Y
S
L
N
E
I
V
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513040
465
52108
T414
L
V
Q
K
T
G
Y
T
L
E
N
L
K
P
C
Chicken
Gallus gallus
P43449
395
44062
L347
C
K
V
T
G
Y
T
L
E
H
I
K
P
C
L
Frog
Xenopus laevis
P47827
415
46651
T367
Y
T
S
Y
T
L
E
T
L
K
P
C
I
L
D
Zebra Danio
Brachydanio rerio
NP_694481
428
47894
S378
L
V
D
L
T
G
Y
S
L
E
D
L
L
P
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P14785
491
56134
K407
L
E
E
I
T
T
Y
K
L
E
D
L
K
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38819
450
50623
T397
P
T
L
E
H
Y
T
T
Y
K
A
S
D
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99
91.4
N.A.
85.4
46.5
N.A.
69.2
63.4
57.6
58.7
N.A.
32.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.3
95.3
N.A.
90.9
60.1
N.A.
76.9
72.2
70.3
69.9
N.A.
48.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
46.6
N.A.
80
0
20
60
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
60
N.A.
100
0
26.6
73.3
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
0
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
9
0
9
67
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
17
0
9
0
9
% D
% Glu:
0
9
9
9
0
0
9
0
9
67
9
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
67
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
25
0
9
0
0
0
0
0
0
9
9
9
0
0
% I
% Lys:
0
9
0
42
0
0
0
9
0
17
0
9
59
0
9
% K
% Leu:
75
0
9
9
0
9
0
9
84
0
0
67
9
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
9
0
9
67
0
% P
% Gln:
0
0
25
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
0
17
0
0
42
9
0
0
0
% S
% Thr:
0
17
0
9
84
9
17
67
0
0
0
0
0
9
0
% T
% Val:
0
25
9
0
0
0
0
0
0
0
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
17
75
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _